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Cyclosporine-induced retinal toxic blindness

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Abstract

We report the case of a BMT recipient who developed blindness 2½ months after BMT. Microvascular retinopathy, cortical blindness and other ocular pathologies were excluded with appropriate tests. Electrophysiological studies showed retinal damage without excluding an optic nerve lesion. The patient, who had several risk factors for neurologic-induced cyclosporine toxicity, improved with cyclosporine withdrawal. Our findings stress the need of electrophysiological tests to exclude neuroretinal damage in patients receiving cyclosporine after BMT.

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Authors and Affiliations

  1. Department of Haematology, Hospital Ramón y Cajal, Universidad de Alcalá de Henares, Madrid, Spain

    J López-Jiménez, A Sánchez, P Herrera & J Odriozola

  2. Department of Ophtalmology, Hospital Ramón y Cajal, Universidad de Alcalá de Henares, Madrid, Spain

    CS Fernández & C Gutiérrez

Authors
  1. J López-Jiménez
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  2. A Sánchez
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  3. CS Fernández
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  4. C Gutiérrez
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  5. P Herrera
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  6. J Odriozola
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López-Jiménez, J., Sánchez, A., Fernández, C. et al. Cyclosporine-induced retinal toxic blindness. Bone Marrow Transplant 20, 243–245 (1997). https://doi.org/10.1038/sj.bmt.1700878

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  • DOI: https://doi.org/10.1038/sj.bmt.1700878

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