Using task-based functional MRI, we examined inpatients with heroin use disorder. We found that 15 weeks of medication-assisted treatment (including supplemental group therapy) improved impaired anterior and dorsolateral prefrontal cortex function during an inhibitory control task. Inhibitory control, a core deficit in drug addiction, may be amenable to targeted prefrontal cortex interventions.
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References
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This is a summary of: Ceceli, A. O. et al. Recovery of anterior prefrontal cortex inhibitory control after 15 weeks of inpatient treatment in heroin use disorder. Nat. Ment. Health https://doi.org/10.1038/s44220-024-00230-4 (2024).
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Prefrontal cortex activity increases after inpatient treatment for heroin addiction. Nat. Mental Health (2024). https://doi.org/10.1038/s44220-024-00239-9
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DOI: https://doi.org/10.1038/s44220-024-00239-9
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