Skip to main content
Log in

Cardiometabolic disease

Biological aging as a predictor of cardiometabolic multimorbidity

  • News & Views
  • Published:

From Nature Cardiovascular Research

View current issue Submit your manuscript

Recent analyses of observational data from 340,000 UK Biobank participants indicate that people with a higher biological age than their same-aged peers have an increased risk of developing cardiometabolic diseases. By contrast, the ability of accelerated biological aging to predict multimorbidity progression is relatively limited.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1: Biological aging and the development of cardiometabolic multimorbidity.

References

  1. Visseren, F. L. J. et al. Eur. Heart J. 42, 3227–3337 (2021).

    Article  PubMed  Google Scholar 

  2. Academy of Medical Sciences. Multimorbidity: a Priority for Global Health Research (2018).

  3. Emerging Risk Factors Collaboration. JAMA 314, 52–60 (2015).

    Article  Google Scholar 

  4. Jiang, M. et al. Nat. Cardiovasc. Res. https://doi.org/10.1038/s44161-024-00438-8 (2024).

    Article  Google Scholar 

  5. Kivimäki, M. et al. Lancet Public Health 2, e277–e285 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Lopez-Otin, C. et al. Cell 186, 243–278 (2023).

    Article  CAS  PubMed  Google Scholar 

  7. Fraser, H. C. et al. Aging Cell 21, e13524 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Singh-Manoux, A. et al. PLoS Med. 15, e1002571 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Rutledge, J., Oh, H. & Wyss-Coray, T. Nat. Rev. Genet. 23, 715–727 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Williams, S. A. et al. Nat. Med. 25, 1851–1857 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Oh, H. S. et al. Nature 624, 164–172 (2023).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mika Kivimäki.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kivimäki, M., Partridge, L. Biological aging as a predictor of cardiometabolic multimorbidity. Nat Cardiovasc Res 3, 256–257 (2024). https://doi.org/10.1038/s44161-024-00444-w

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s44161-024-00444-w

  • Springer Nature Limited

Navigation