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Challenges and opportunities for biomarker discovery to predict imminent myocardial infarction

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In coronary artery disease, the transition from an apparently stable state to a life-threatening acute cardiac event is difficult to predict. As such, a recent study applied proteomic and metabolomic approaches to discover new biomarkers that signal imminent myocardial infarction.

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Acknowledgements

D.M.K. is supported by a British Heart Foundation Intermediate Basic Science Research Fellowship (FS/IBSRF/23/25161). N.L.M. is supported by a Chair Award (CH/F/21/90010), Programme Grant (RG/20/10/34966) and a Research Excellent Award (RE/18/5/34216) from the British Heart Foundation.

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Authors and Affiliations

  1. BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK

    Marie de Bakker, Dorien M. Kimenai & Nicholas L. Mills

  2. Usher Institute, University of Edinburgh, Edinburgh, UK

    Nicholas L. Mills

Authors
  1. Marie de Bakker
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  2. Dorien M. Kimenai
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  3. Nicholas L. Mills
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Correspondence to Nicholas L. Mills.

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Competing interests

N.L.M. reports receiving research grants awarded to the University of Edinburgh from Abbott Diagnostics, Siemens Healthineers and Roche Diagnostics unrelated to this work, and honoraria from Abbott Diagnostics, Siemens Healthineers, Roche Diagnostics, LumiraDx and Psyros Diagnostics.

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de Bakker, M., Kimenai, D.M. & Mills, N.L. Challenges and opportunities for biomarker discovery to predict imminent myocardial infarction. Nat Cardiovasc Res 3, 102–103 (2024). https://doi.org/10.1038/s44161-024-00424-0

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