Cerebrospinal fluid is now thought to drain through lymphatics instead of veins, but the routes the fluid takes from the subarachnoid space to cervical lymph nodes are unclear. Using advanced imaging, a recent study provides unprecedented anatomical details of lymphatic vessels draining cerebrospinal fluid along the nasopharynx.
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References
Proulx, S. T. Cell Mol. Life Sci. 78, 2429–2457 (2021).
Ma, Q. et al. Nat. Commun. 8, 1434 (2017).
Louveau, A. et al. J. Clin. Invest. 127, 3210–3219 (2017).
Key, A. & Retzius, G. Studien in der Anatomie des Nervensystems und des Bindegewebes (Samson & Wallin, 1875).
Spera, I. et al. EBioMedicine 91, 104558 (2023).
Rustenhoven, J. & Kipnis, J. Science 366, 1448–1449 (2019).
Melin, E. et al. Sci. Rep. 10, 14974 (2020).
Yoon, J.-H. et al. Nature https://doi.org/10.1038/s41586-023-06899-4 (2024).
Decker, Y. et al. JCI Insight 7, e150881 (2022).
de Leon, M. J. et al. J. Nucl. Med. 58, 1471–1476 (2017).
Zhou, Y. et al. EBioMedicine 86, 104381 (2022).
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Spera, I., Proulx, S.T. A nasal hub for cerebrospinal fluid clearance. Nat Cardiovasc Res 3, 98–99 (2024). https://doi.org/10.1038/s44161-024-00423-1
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DOI: https://doi.org/10.1038/s44161-024-00423-1
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