An algorithm is presented for the simulation of reaction–diffusion systems on complex geometries, providing insight on how the interplay of cell geometry and biochemistry can control polarity in living cells.
References
St Johnston, D. Curr. Opin. Cell Biol. 51, 33–41 (2018).
Devreotes, P. & Horwitz, A. R. Cold Spring Harb. Perspect. Biol. 7, a005959 (2015).
Chiou, J. G., Balasubramanian, M. K. & Lew, D. J. Annu. Rev. Cell Dev. Biol. 33, 77–101 (2017).
Zamparo, M. et al. Soft Matter 11, 838–849 (2015).
Miller, P. W., Fortunato, D., Muratov, C., Greengard, L. & Shvartsman, S. Nat. Comput. Sci. https://doi.org/10.1038/s43588-022-00295-0 (2022).
Thalmeier, D., Halatek, J. & Frey, E. Proc. Natl Acad. Sci. USA 113, 548–553 (2016).
Diegmiller, R., Montanelli, H., Muratov, C. B. & Shvartsman, S. Y. Biophys. J. 115, 26–30 (2018).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing interests.
Rights and permissions
About this article
Cite this article
Di Talia, S. Geometry and symmetry-breaking in cell polarity. Nat Comput Sci 2, 473–474 (2022). https://doi.org/10.1038/s43588-022-00304-2
Published:
Issue Date:
DOI: https://doi.org/10.1038/s43588-022-00304-2
- Springer Nature America, Inc.