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Revisiting colocalization via optimal transport

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The advent of STED microscopy, which allows observation at a sub-diffraction resolution, raises a challenge in studying spatial proximities of biomolecules’ distributions. In this issue, researchers have attempted to study colocalization of molecules by employing optimal transport.

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Fig. 1: Challenges in colocalization quantification and new colocalization measure proposed by Carla Tameling and colleagues.

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Authors and Affiliations

  1. Department of Statistics, University of Illinois at Urbana-Champaign, Champaign, IL, USA

    Shulei Wang

  2. Department of Statistics, Columbia University, New York, NY, USA

    Ming Yuan

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  1. Shulei Wang
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  2. Ming Yuan
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Correspondence to Shulei Wang.

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The authors declare no competing interests.

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Wang, S., Yuan, M. Revisiting colocalization via optimal transport. Nat Comput Sci 1, 177–178 (2021). https://doi.org/10.1038/s43588-021-00046-7

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