Staging Alzheimer’s disease on the basis of the disease’s biological underpinnings might help with stratification and prognostication, both in the clinical setting and in clinical trials. We propose a staging model based on only five biomarkers, which are related to amyloid-β and tau pathologies in different ways and can be measured with a single sample of cerebrospinal fluid.
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References
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This is a summary of: Salvadó, G. et al. Disease staging of Alzheimer’s disease using a CSF-based biomarker model. Nat. Aging https://doi.org/10.1038/s43587-024-00599-y (2024).
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Five biomarkers from one cerebrospinal fluid sample to stage Alzheimer’s disease. Nat Aging (2024). https://doi.org/10.1038/s43587-024-00618-y
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DOI: https://doi.org/10.1038/s43587-024-00618-y
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