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Alzheimer’s disease

Intermittent fasting to slow down Alzheimer’s disease

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In our aging global population and with no effective treatments, the cognitive impairments associated with Alzheimer’s disease represent a major healthcare problem. A recent study in Nature Aging highlights intermittent fasting as a potential way to decrease the progression of Alzheimer’s disease in mice through changes to the gut microbiota.

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Fig. 1: IF attenuates amyloid pathology and cognitive impairment in a mouse model of AD through changes in the microbiota–gut–brain axis.

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Acknowledgements

The authors receive funding from Science Foundation Ireland (SFI) under grant number SFI/FFP/6820. Y.M.N. is funded Investigator of the APC Microbiome Ireland.

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Authors and Affiliations

  1. Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland

    Sarah Nicolas & Yvonne M. Nolan

  2. APC Microbiome Ireland, University College Cork, Cork, Ireland

    Sarah Nicolas & Yvonne M. Nolan

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  1. Sarah Nicolas
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  2. Yvonne M. Nolan
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Correspondence to Yvonne M. Nolan.

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Nicolas, S., Nolan, Y.M. Intermittent fasting to slow down Alzheimer’s disease. Nat Aging 2, 982–983 (2022). https://doi.org/10.1038/s43587-022-00320-x

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