Our longitudinal study comparing the skin, gut and oral microbiomes of community-dwelling older adults and nursing home residents showed striking changes known to be linked to antibiotic resistance and disease risk. Such shifts were associated with frailty, not chronological age, and were most pronounced in the skin, the primary reservoir for infection risk.
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This is a summary of: Larson, P. J. et al. Associations of the skin, oral and gut microbiome with aging, frailty and infection risk reservoirs in older adults. Nat. Aging https://doi.org/10.1038/s43587-022-00287-9 (2022).
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Frailty-associated dysbiosis of human microbiotas in older adults in nursing homes. Nat Aging 2, 876–877 (2022). https://doi.org/10.1038/s43587-022-00289-7
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DOI: https://doi.org/10.1038/s43587-022-00289-7
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