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Homme fatal: how males cause demise

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While C. elegans males are known to induce demise of hermaphrodites, the mechanism underlying this phenomenon is poorly understood. Through transcriptomic analyses, Booth et al. identify specific hermaphrodite gene sets that respond to male pheromones, sperm and seminal fluid and can mediate premature death of hermaphrodites.

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Fig. 1: Males cause hermaphrodite demise through multiple ways.

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Authors and Affiliations

  1. Department of Biological Sciences, Wayne State University, Detroit, MI, USA

    Deniz Sifoglu & Joy Alcedo

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  1. Deniz Sifoglu
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  2. Joy Alcedo
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Correspondence to Joy Alcedo.

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The authors declare no competing interests.

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Sifoglu, D., Alcedo, J. Homme fatal: how males cause demise. Nat Aging 2, 773–774 (2022). https://doi.org/10.1038/s43587-022-00274-0

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