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Alzheimer’s amyloid-β drug hangs in the balance

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The latest spat over the potential approval of aducanumab, an amyloid-β-targeting drug for Alzheimer’s disease, highlights continuing controversy over the amyloid-β hypothesis.

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References

  1. Massie, T. Statistical review aducanumab in Alzheimer’s. FDA https://collaboration.fda.gov/pradgevcxis7 (2020).

  2. Mintun, M. A. et al. New Engl. J. Med. https://doi.org/10.1056/NEJMoa2100708 (2021).

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Correspondence to Mark Zipkin.

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Zipkin, M. Alzheimer’s amyloid-β drug hangs in the balance. Nat Aging 1, 324–326 (2021). https://doi.org/10.1038/s43587-021-00059-x

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  • DOI: https://doi.org/10.1038/s43587-021-00059-x

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