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DIET AND HEALTH

Nutrition’s dark matter of polyphenols and health

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Food contains thousands of different trace natural compounds, many of which remain largely unmeasured and undocumented. The network medicine approach sheds new light on how polyphenols, among the most important of these trace compounds, impact human health.

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Fig. 1: The impacts on human health of flavonoids, phenolic acids, phenolic amides, and other polyphenols found in foods are largely unexplored, and may benefit from a network medicine approach.

References

  1. Wang, D. D. et al. J. Nutr. 149, 1065–1074 (2019).

    Article  Google Scholar 

  2. Scotece, M. et al. Drug Discov. Today 20, 406–410 (2015).

    Article  CAS  Google Scholar 

  3. Mozaffarian, D. & Wu, J. H. Y. Circ. Res. 122, 369–384 (2018).

    Article  CAS  Google Scholar 

  4. do Valle, I. F. et al. Nat. Food https://doi.org/10.1038/s43016-021-00243-7 (2021).

  5. Kawser Hossain, M. et al. Int. J. Mol. Sci. 17, 569 (2016).

    Article  Google Scholar 

  6. Warner, E. F. et al. J. Nutr. 146, 465–473 (2016).

    Article  CAS  Google Scholar 

  7. Cassidy, A. & Minihane, A. M. Am. J. Clin. Nutr. 105, 10–22 (2017).

    Article  CAS  Google Scholar 

  8. Goya, L. et al. Nutrients 8, 212 (2016).

    Article  Google Scholar 

  9. Fleischhacker, S. E. et al. Am. J. Clin. Nutr. 112, 721–769 (2020).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA

    Dariush Mozaffarian

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  1. Dariush Mozaffarian
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Correspondence to Dariush Mozaffarian.

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Competing interests

This work was supported by the National Institutes of Health (R01 HL115189). The author also reports, outside of this work, research support from the Gates Foundation and the Rockefeller Foundation; personal fees from Acasti Pharma, Amarin, America’s Test Kitchen, Barilla, Cleveland Clinic Foundation, Danone, GOED, and Motif FoodWorks; scientific advisory board, Beren Therapeutics, Brightseed, Calibrate, DayTwo, Elysium Health, Filtricine, Foodome, HumanCo, January Inc., and Tiny Organics; and chapter royalties from UpToDate.

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Mozaffarian, D. Nutrition’s dark matter of polyphenols and health. Nat Food 2, 139–140 (2021). https://doi.org/10.1038/s43016-021-00248-2

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