Methionine restriction modulates tumour growth and ageing processes through its influence on diverse metabolic processes. Ji et al. demonstrate that methionine restriction compromises production of hydrogen sulfide (H2S), which impairs H2S-mediated immune signalling and results in increased cancer progression in immunocompetent mice.
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Joulia, E., Metallo, C.M. Methionine and H2S alter cancer–immune dialogue. Nat Metab 5, 1456–1458 (2023). https://doi.org/10.1038/s42255-023-00862-3
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DOI: https://doi.org/10.1038/s42255-023-00862-3
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