An elegant quantitative analysis of brown fat and skeletal muscle metabolite flux reveals unpredicted fuel usage during thermogenesis, which suggests that brown fat predominantly uses glucose and lactate and acts as a nitrogen scavenger.
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Acknowledgements
A.B. was supported by the German Center for Cardiovascular Research (DZHK) and the ERC Starting Grant PROTEOFIT.
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I.L.L. wrote the manuscript and created the original figure with the help of A.B. Both authors read and commented on the manuscript.
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Lemmer, I.L., Bartelt, A. Brown fat has a sweet tooth. Nat Metab 5, 1080–1081 (2023). https://doi.org/10.1038/s42255-023-00824-9
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DOI: https://doi.org/10.1038/s42255-023-00824-9
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