Most of human microbiome research has focused on analysing faecal samples, which represent the final stop of the digestive journey. Two recent articles use a novel sampling approach to capture luminal content at different points during digestion and reveal that the analysis of faecal samples tells only a fraction of the story.
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Quinn, R.A., Martin, C. & Guzior, D.V. A multi-omic trip through the human gut. Nat Metab 5, 720–721 (2023). https://doi.org/10.1038/s42255-023-00773-3
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DOI: https://doi.org/10.1038/s42255-023-00773-3
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