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VASCULAR DISEASE

Lnc-ing microRNA activity to atheroprotection

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Cholesterol accumulation in cells and blood vessels promotes the development of vascular diseases. The long non-coding RNA CHROME can help clear excess cholesterol and provide protection from atherosclerosis.

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Fig. 1: Model for CHROME actions in atherosclerosis.

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Authors and Affiliations

  1. Department of Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, CA, USA

    Tamer Sallam

  2. Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, USA

    Peter Tontonoz

Authors
  1. Tamer Sallam
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  2. Peter Tontonoz
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Correspondence to Peter Tontonoz.

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The authors declare no competing interests.

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Sallam, T., Tontonoz, P. Lnc-ing microRNA activity to atheroprotection. Nat Metab 1, 10–11 (2019). https://doi.org/10.1038/s42255-018-0012-9

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