The chemical synthesis of natural products, such as sesquiterpenes, is a daunting task due to their complexity and precise functionalization, and multiple synthetic and purification steps that reduce overall yields are usually required. Now, a highly efficient alternative approach using supramolecular chemistry has been proposed by Tiefenbacher and co-workers.
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Major, D.T. Complex terpenes in one pot. Nat Catal 1, 567–568 (2018). https://doi.org/10.1038/s41929-018-0130-5
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DOI: https://doi.org/10.1038/s41929-018-0130-5
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