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The well-built research question

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Lab Animal

How to reduce animal numbers and increase the information content of animal-based studies. A ‘well-built’ research question turns the research hypothesis into an actionable, focused, and testable plan of action.

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Fig. 1: System diagram for the ‘well-built’ research question PICOT.

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Authors and Affiliations

  1. Department of Anesthesiology, University of Florida, Gainesville, FL, USA

    Penny Reynolds

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  1. Penny Reynolds
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Correspondence to Penny Reynolds.

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The author declares no competing interest.

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Reynolds, P. The well-built research question. Lab Anim 52, 221–223 (2023). https://doi.org/10.1038/s41684-023-01257-3

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