Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments

Table 1 Correlation between the target proteins and tumor-infiltrating immune cells.

Gene name	Parameters	Purity	B cell	CD8⁺	CD4⁺	Macrophage	Neutrophil	Dendritic cell
AKT1	R	0.311	0.013	− 0.318	0.187	− 0.008	− 0.127	0.134
AKT1	P value	0.000206	0.878	0.000153	0.0287	0.924	0.14	0.119
EGFR	R	0.288	0.07	− 0.142	0.195	− 0.04	0.005	0.041
EGFR	P value	0.000615	0.417	0.0975	0.0227	0.639	0.957	0.63
CASP3	R	0.232	− 0.181	0.033	− 0.103	− 0.163	0.009	0.027
CASP3	P value	0.00624	0.0344	0.705	0.231	0.0563	0.917	0.751
MMP9	R	− 0.164	− 0.004	0.128	− 0.263	0.019	0.06	0.147
MMP9	P value	0.0546	0.961	0.135	0.0019	0.822	0.484	0.0858