Here we investigate the role of epigenetics in the formation, transcription regulation, maintenance and termination of several non-canonical chromatin structures. Using two examples, we demonstrate how studying non-canonical structures may reveal underlying mechanisms with implications for disease and propose intriguing epigenetic avenues for further exploration.
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Agustinus, A.S., David, Y. Thinking outside the chromosome: epigenetic mechanisms in non-canonical chromatin species. Nat Struct Mol Biol 31, 8–10 (2024). https://doi.org/10.1038/s41594-023-01200-7
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DOI: https://doi.org/10.1038/s41594-023-01200-7
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