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Inefficient splicing curbs noncoding RNA transcription

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An Author Correction to this article was published on 01 April 2021

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Pervasive genome-wide transcription initiation by RNA polymerase II (Pol II) necessitates mechanisms that restrain the quantity and length of the transcripts. A new study investigates a mechanism for inducing early transcription termination, employed primarily at genomic regions producing noncoding RNAs.

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Fig. 1: The WDR82–ZC3H4 complex curbs noncoding RNA transcription.

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Authors and Affiliations

  1. Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

    Noa Gil

  2. Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel

    Igor Ulitsky

Authors
  1. Noa Gil
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  2. Igor Ulitsky
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Correspondence to Noa Gil or Igor Ulitsky.

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The authors declare no competing interests.

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Gil, N., Ulitsky, I. Inefficient splicing curbs noncoding RNA transcription. Nat Struct Mol Biol 28, 327–328 (2021). https://doi.org/10.1038/s41594-021-00582-w

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