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Protein shapes at the core of chronic traumatic encephalopathy

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A Publisher Correction to this article was published on 23 May 2019

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A recent cryo-EM study has generated breakthrough insights into the molecular and structural bases of tau tangles from individuals who died of CTE.

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Fig. 1: Structures of tau filaments extracted from brains of people diagnosed with tauopathies.
Fig. 2: Cofactors might be part of the tau filament assembly process.

Change history

  • 23 May 2019

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Acknowledgements

Y.F. is supported by the National Institute of Aging of the US National Institutes of Health (NIH) through grant R01AG05605. S.H. acknowledges support of that NIH grant R01AG05605 and the Tau Consortium of the Rainwater Charitable Foundation.

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Authors and Affiliations

  1. Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, CA, USA

    Yann Fichou & Songi Han

  2. Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA, USA

    Songi Han

  3. Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, CA, USA

    Songi Han

Authors
  1. Yann Fichou
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  2. Songi Han
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Correspondence to Songi Han.

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The authors declare no competing interests.

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Fichou, Y., Han, S. Protein shapes at the core of chronic traumatic encephalopathy. Nat Struct Mol Biol 26, 336–338 (2019). https://doi.org/10.1038/s41594-019-0221-2

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