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ASTROCYTES

Diving into new depths of astrocyte signaling

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Astrocytes are crucial contributors to brain homeostasis. Yet the lack of ad hoc analysis tools has prevented in-depth characterization of astrocyte-derived signals. In a new study, the authors present an image-analysis toolbox that captures the complexity of astrocyte activity and enables our understanding of astrocytic physiology.

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Fig. 1: Event-based data analysis of astrocytic activity with AQuA.

References

  1. Khakh, B. S. & Sofroniew, M. V. Nat. Neurosci. 18, 942–952 (2015).

    Article  CAS  Google Scholar 

  2. Santello, M., Toni, N. & Volterra, A. Nat. Neurosci. 22, 154–166 (2019).

    Article  CAS  Google Scholar 

  3. Wang, X. et al. Nat. Neurosci. 9, 816–823 (2006).

    Article  CAS  Google Scholar 

  4. Wang, Y. et al. Nat. Neurosci. https://doi.org/10.1038/s41593-019-0492-2 (2019).

  5. Otsu, Y. et al. Nat. Neurosci. 18, 210–218 (2015).

    Article  CAS  Google Scholar 

  6. Khakh, B. S. & McCarthy, K. D. Cold Spring Harb. Perspect. Biol. 7, a020404 (2015).

    Article  Google Scholar 

  7. Bindocci, E. et al. Science 356, eaai8185 (2017).

    Article  Google Scholar 

  8. Stobart, J. L. et al. Neuron 98, 726–735.e4 (2018).

    Article  CAS  Google Scholar 

  9. Volterra, A., Liaudet, N. & Savtchouk, I. Nat. Rev. Neurosci. 15, 327–335 (2014).

    Article  CAS  Google Scholar 

  10. Paukert, M. et al. Neuron 82, 1263–1270 (2014).

    Article  CAS  Google Scholar 

  11. Marvin, J. S. et al. Nat. Methods 10, 162–170 (2013).

    Article  CAS  Google Scholar 

  12. Haustein, M. D. et al. Neuron 82, 413–429 (2014).

    Article  CAS  Google Scholar 

  13. Romanos, J., Benke, D., Saab, A. S., Zeilhofer, H. U. & Santello, M. Commun. Biol. 2, 127 (2019).

    Article  Google Scholar 

  14. Marvin, J. S. et al. Nat. Methods 16, 763–770 (2019).

    Article  CAS  Google Scholar 

  15. Feng, J. et al. Neuron 102, 745–761.e8 (2019).

    Article  CAS  Google Scholar 

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Correspondence to Mirko Santello.

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Romanos, J., Thieren, L. & Santello, M. Diving into new depths of astrocyte signaling. Nat Neurosci 22, 1749–1750 (2019). https://doi.org/10.1038/s41593-019-0513-1

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