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How old is your brain?

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Using data from 45,615 people, Kaufmann et al. compare the gaps between brain age and chronological age in a number of brain disorders and study the relationship of these gaps with genetics. Their research shows that the brains of individuals with a range of different brain disorders, such as dementia and schizophrenia, are aging faster than normal.

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Fig. 1: Calculating the brain age gap.

References

  1. Cole, J. H. & Franke, K. Trends Neurosci. 40, 681–690 (2017).

    Article  CAS  Google Scholar 

  2. Kaufmann, T., van der Meer, D., Doan, N.T., Schwarz, E. & Lund, M.J. Nat. Neurosci. https://doi.org/10.1038/s41593-019-0471-7 (2019).

  3. Gratten, J. & Visscher, P. M. Genome Med. 8, 78 (2016).

    Article  Google Scholar 

  4. Insel, T. R. Am. J. Psychiatry 171, 395–397 (2014).

    Article  Google Scholar 

  5. Miller, K. L. et al. Nat. Neurosci. 19, 1523–1536 (2016).

    Article  CAS  Google Scholar 

  6. Thompson, P. M. et al. Neuroimage 145 Pt B, 389–408 (2017).

    Article  Google Scholar 

  7. Weiner, M. W. et al. Alzheimers Dement. 13, e1–e85 (2017).

    Article  Google Scholar 

  8. Smith, S. M. & Nichols, T. E. Neuron 97, 263–268 (2018).

    Article  CAS  Google Scholar 

  9. Fortin, J.-P. et al. Neuroimage 167, 104–120 (2018).

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, Washington University Medical School, Saint Louis, Missouri, USA

    Janine Bijsterbosch

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  1. Janine Bijsterbosch
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Correspondence to Janine Bijsterbosch.

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Bijsterbosch, J. How old is your brain?. Nat Neurosci 22, 1611–1612 (2019). https://doi.org/10.1038/s41593-019-0478-0

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