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Single-cell probing of RNA structure

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sc-SPORT offers a way to probe RNA structure at the single-cell level. It reveals cell-to-cell heterogeneity in RNA folding.

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Fig. 1: sc-SPORT.

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Acknowledgements

This work was supported by funds from the National Institute of Health grant R35- GM127064 (P.C.B.).

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Authors and Affiliations

  1. Department of Chemistry, Pennsylvania State University, University Park, PA, USA

    Elizabeth A. Jolley & Philip C. Bevilacqua

  2. Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA, USA

    Elizabeth A. Jolley & Philip C. Bevilacqua

  3. Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA

    Philip C. Bevilacqua

Authors
  1. Elizabeth A. Jolley
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  2. Philip C. Bevilacqua
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Correspondence to Philip C. Bevilacqua.

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The authors declare no competing interests.

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Jolley, E.A., Bevilacqua, P.C. Single-cell probing of RNA structure. Nat Methods 21, 377–378 (2024). https://doi.org/10.1038/s41592-024-02178-w

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