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Expanding RNA target effectors

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Researchers identified a single-effector Cas, Cas7-11, that architecturally diverges from previous CRISPR single- or multi-component systems and can possess RNA knockdown activity without detectable collateral activity in mammalian cells.

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Research paper

  • Özcan, A. et al. Programmable RNA targeting with the single-protein CRISPR effector Cas7-11. Nature 597, 720–725 (2021).

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  1. Nature Methods http://www.nature.com/nmeth

    Lei Tang

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  1. Lei Tang
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Correspondence to Lei Tang.

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Tang, L. Expanding RNA target effectors. Nat Methods 18, 1276 (2021). https://doi.org/10.1038/s41592-021-01323-z

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  • DOI: https://doi.org/10.1038/s41592-021-01323-z

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