Microfluidic channels provide a means to deliver barcodes encoding spatial information to a tissue, which allows co-profiling of gene expression and proteins of interest in a spatially resolved manner.
Research paper
Liu, Y. et al. High-spatial-resolution multi-omics sequencing via deterministic barcoding in tissue. Cell https://doi.org/10.1016/j.cell.2020.10.026 (2020).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Tang, L. Multiomics sequencing goes spatial. Nat Methods 18, 31 (2021). https://doi.org/10.1038/s41592-020-01043-w
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41592-020-01043-w
- Springer Nature America, Inc.
This article is cited by
-
Microtechnologies for single-cell and spatial multi-omics
Nature Reviews Bioengineering (2023)