In a clinical trial, non-nutritive sweeteners — which are supposedly inert — were shown to disrupt the gut microbiome of healthy people and impair glucose tolerance.
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Le Roy, T., Clément, K. Bittersweet: artificial sweeteners and the gut microbiome. Nat Med 28, 2259–2260 (2022). https://doi.org/10.1038/s41591-022-02063-z
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DOI: https://doi.org/10.1038/s41591-022-02063-z
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