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Liquid biopsies and tumor mutational burden: the cutoff conundrum

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Assessment of tumor mutational burden through a simple blood test could help to identify which patients are most likely to benefit from immunotherapy, but optimal cutoffs are not well established.

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Fig. 1: Tumor mutational burden in blood and tissue.

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Correspondence to Pashtoon Murtaza Kasi.

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Kasi, P.M. Liquid biopsies and tumor mutational burden: the cutoff conundrum. Nat Med 28, 1753–1754 (2022). https://doi.org/10.1038/s41591-022-01999-6

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