Skip to main content

Advertisement

SpringerLink
Log in

LIVER DISEASE

Omics and AI advance biomarker discovery for liver disease

  • News & Views
  • Published:

From Nature Medicine

View current issue Submit your manuscript

New technologies allow the noninvasive detection and staging of asymptomatic alcohol-associated liver disease; further refinement of this approach could transform clinical management and improve patient outcomes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: Conceptual model of the future of liver-disease management.

References

  1. GBD 2017 Cirrhosis Collaborators. Lancet Gastroenterol. Hepatol. 5, 245–266 (2020).

    Article  Google Scholar 

  2. Singal, A. K. & Mathurin, P. J. Am. Med. Assoc. 326, 165–176 (2021).

    Article  CAS  Google Scholar 

  3. Niu, L. et al. Nat. Med. https://doi.org/10.1038/s41591-022-01850-y (2022).

    Article  PubMed  Google Scholar 

  4. Ahn, J. C. et al. Hepatology 73, 2546–2563 (2021).

    Article  Google Scholar 

  5. Yip, T. C. et al. Aliment. Pharmacol. Ther. 46, 447–456 (2017).

    Article  CAS  Google Scholar 

  6. Ioannou, G. N. et al. JAMA Netw. Open https://doi.org/10.1001/jamanetworkopen.2020.15626 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Ahn, J. C. et al. Am. J. Gastroenterol. 117, 424–432 (2022).

    Article  Google Scholar 

  8. Forlano, R. et al. Clin. Gastroenterol. Hepatol. 18, 2081–2090 (2020).

    Article  Google Scholar 

  9. Morshid, A. et al. Radiol. Artif. Intell. https://doi.org/10.1148/ryai.2019180021 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  10. Boehm, K. M. et al. Nat. Rev. Cancer 22, 114–126 (2022).

    Article  CAS  Google Scholar 

  11. Galior, K. et al. Bonekey Rep. 8, 268–273 (2018).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA

    Tiffany Wu & Vijay H. Shah

  2. Department of Biochemistry and Molecular Biology, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN, USA

    Shawna A. Cooper

Authors
  1. Tiffany Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Shawna A. Cooper
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Vijay H. Shah
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vijay H. Shah.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wu, T., Cooper, S.A. & Shah, V.H. Omics and AI advance biomarker discovery for liver disease. Nat Med 28, 1131–1132 (2022). https://doi.org/10.1038/s41591-022-01853-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41591-022-01853-9

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation