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Local cellular cues that influence the immunology of colorectal cancer treatment

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Therapeutic interventions in colorectal cancer are dependent on immune responses to dying epithelial cells that are modulated by specific members of the gut microbiota.

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Fig. 1: A link among apoptosis, the microbiome and immune responses in the treatment of colorectal cancer.

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Correspondence to Gregory P. Donaldson or Daniel Mucida.

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Donaldson, G.P., Mucida, D. Local cellular cues that influence the immunology of colorectal cancer treatment. Nat Med 26, 824–826 (2020). https://doi.org/10.1038/s41591-020-0902-8

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