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NKT cells

Unconventional haircare

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A specialized subset of iNKT cells populates the skin in early life, where their supply of transferrin regulates iron metabolism to promote hair follicle development.

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Fig. 1: CCR10+ iNKT cells support hair follicle development by local provision of transferrin.

References

  1. Mayassi, T., Barreiro, L. B., Rossjohn, J. & Jabri, B. Nature 595, 501–510 (2021).

    Article  CAS  Google Scholar 

  2. Constantinides, M. G. & Belkaid, Y. Science 374, eabf0095 (2021).

    Article  CAS  Google Scholar 

  3. Wang, W.-B. et al. Nat. Immunol. https://doi.org/10.1038/s41590-022-01399-5 (2023).

  4. Crosby, C. M. & Kronenberg, M. Nat. Rev. Immunol. 18, 559–574 (2018).

    Article  CAS  Google Scholar 

  5. Xiong, N., Fu, Y., Hu, S., Xia, M. & Yang, J. Protein Cell 3, 571–580 (2012).

    Article  CAS  Google Scholar 

  6. Havran, W. L. & Jameson, J. M. J. Immunol. 184, 5423–5428 (2010).

    Article  CAS  Google Scholar 

  7. An, D. et al. Cell 156, 123–133 (2014).

    Article  CAS  Google Scholar 

  8. Almohanna, H. M., Ahmed, A. A., Tsatalis, J. P. & Tosti, A. Dermatol. Ther. (Heidelb) 9, 51–70 (2019).

    Article  Google Scholar 

  9. Wright, J. A., Richards, T. & Srai, S. K. Front. Pharmacol. 5, 156 (2014).

    Article  Google Scholar 

  10. Cox, J. R., Cruickshank, S. M. & Saunders, A. E. Front. Immunol. 12, 670471 (2021).

    Article  CAS  Google Scholar 

  11. Rahmani, W., Sinha, S. & Biernaskie, J. NPJ Regen. Med. 5, 9 (2020).

    Article  Google Scholar 

  12. Ataide, M. A. et al. Immunity 55, 1813–1828 e1819 (2022).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia

    Hui-Fern Koay & Laura K. Mackay

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  1. Hui-Fern Koay
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  2. Laura K. Mackay
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Correspondence to Laura K. Mackay.

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The authors declare no competing interests.

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Koay, HF., Mackay, L.K. Unconventional haircare. Nat Immunol 24, 211–212 (2023). https://doi.org/10.1038/s41590-022-01411-y

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