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INNATE LYMPHOID CELLS

Neuropilin-1 flags lung-resident type 2 innate lymphoid cells

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Type 2 innate lymphoid cells (ILC2s) are implicated in lung diseases such as idiopathic pulmonary fibrosis, but targeting these cells is a challenge. New data show that neuropilin-1 drives the ILC2 phenotype and is specific to lung-resident ILC2s in mice.

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Fig. 1: Model of Nrp1 involvement in ILC2 function in experimental lung fibrosis.

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Correspondence to Hergen Spits.

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Spits, H. Neuropilin-1 flags lung-resident type 2 innate lymphoid cells. Nat Immunol 23, 151–152 (2022). https://doi.org/10.1038/s41590-021-01115-9

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