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Parsing the transcription factors governing T cell immunity

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Zhong et al. exploit allelic variations in mice to pinpoint the ‘heavy lifter’ transcription factor families governing the chromatin landscape of resting and activated T cells.

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Fig. 1: Identifying the heavy lifter transcription factors that regulate the chromatin and transcriptional landscape during T cell activation.

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Authors and Affiliations

  1. The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia

    Timothy M. Johanson & Rhys S. Allan

  2. Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia

    Timothy M. Johanson & Rhys S. Allan

Authors
  1. Timothy M. Johanson
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  2. Rhys S. Allan
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Correspondence to Rhys S. Allan.

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The authors declare no competing interests.

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Johanson, T.M., Allan, R.S. Parsing the transcription factors governing T cell immunity. Nat Immunol 23, 3–4 (2022). https://doi.org/10.1038/s41590-021-01075-0

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