Epigenetic modifications are associated with distinct stages of autoreactive CD8+ T cell differentiation. DNA methylation and chromatin changes guide the acquisition of a memory-like phenotype and sustain prolonged autoimmune effector responses.
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Petiti, L., Pace, L. The persistence of stemness. Nat Immunol 21, 492–494 (2020). https://doi.org/10.1038/s41590-020-0644-2
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DOI: https://doi.org/10.1038/s41590-020-0644-2
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