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IL-17 instructs lymphoid stromal cells

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The cytokine IL-17 augments metabolism in fibroblastic reticular cells in lymph nodes, which enhances their proliferation and survival to support B cell responses during autoimmunity.

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Fig. 1: IL-7 augments responses by activated FRCs.

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Correspondence to Scott N. Mueller.

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Mueller, S.N. IL-17 instructs lymphoid stromal cells. Nat Immunol 20, 524–526 (2019). https://doi.org/10.1038/s41590-019-0375-4

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