The metabolic master regulator mTORC1 is shown to promote alternative macrophage activation via Semaphorin 6D reverse signaling and reprogramming of lipid metabolism.
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Wilson, J.L., Weichhart, T. TORching a semaphore for alternative macrophage activation. Nat Immunol 19, 512–514 (2018). https://doi.org/10.1038/s41590-018-0117-z
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DOI: https://doi.org/10.1038/s41590-018-0117-z
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