Skip to main content
SpringerLink
Log in

HUMAN INFLUENZA

Influenza’s signature move

  • News & Views
  • Published:

From Nature Immunology

View current issue Submit your manuscript

Analysis of whole-blood transcriptional profiles in adults hospitalized with influenza reveals time- and severity-related gene-expression signatures.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: The gene-expression pattern in influenza virus–infected patients reflects the severity of disease and time since infection.

References

  1. Iuliano, A.D. et al. Lancet 391, 1285–1300 (2018).

    Article  PubMed  Google Scholar 

  2. Rynda-Apple, A., Robinson, K. M. & Alcorn, J. F. Infect. Immun. 83, 3764–3770 (2015).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  3. Dunning, J. et al. Nat. Immunol. https://doi.org/10.1038/s41590-018-0111-5 (2018).

  4. Woods, C. W. et al. PLoS One 8, e52198 (2013).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Ramilo, O. et al. Blood 109, 2066–2077 (2007).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  6. Zaas, A. K. et al. Cell Host Microbe 6, 207–217 (2009).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  7. Chaussabel, D. et al. Immunity 29, 150–164 (2008).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  8. Schliehe, C. et al. Nat. Immunol. 16, 67 (2014).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Epigenetics Discovery Performance Unit, Oncology and Immunoinflammation Therapy Area Units, GSK Medicines Research Centre, Stevenage, UK

    David F. Tough

Authors
  1. David F. Tough
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to David F. Tough.

Ethics declarations

Competing interests

D.F.T. is an employee and shareholder of GlaxoSmithKline, which is involved in the research and development of medicines for the treatment of human disease.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tough, D.F. Influenza’s signature move. Nat Immunol 19, 518–520 (2018). https://doi.org/10.1038/s41590-018-0115-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41590-018-0115-1

  • Springer Nature America, Inc.

Search

Navigation