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Ferroptosis

A radical way to avoid cell death

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Ferroptosis is a mechanism of cell death that has possible roles in numerous diseases. Two new studies have identified hydropersulfides as potent inhibitors of O2-dependent membrane damage and destruction, and as potential regulators of ferroptosis.

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Fig. 1: Mechanism of ferroptosis.

References

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Authors and Affiliations

  1. Department of Chemistry, Sonoma State University, Rohnert Park, CA, USA

    Jon M. Fukuto

  2. Department of Chemistry, Johns Hopkins University, Baltimore, MD, USA

    Jon M. Fukuto

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  1. Jon M. Fukuto
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Correspondence to Jon M. Fukuto.

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Fukuto, J.M. A radical way to avoid cell death. Nat Chem Biol 19, 1–2 (2023). https://doi.org/10.1038/s41589-022-01174-5

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  • DOI: https://doi.org/10.1038/s41589-022-01174-5

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