Natural enzyme complexes can rapidly change configurations to respond to intracellular cues. Now CRISPR enzymes and programmable RNA scaffolds allow synthetic enzyme complexes to be assembled and disassembled on demand.
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A.A.G. is a cofounder of En Carta Diagnostics.
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Green, A.A. Enzyme assemblies on demand. Nat Chem Biol 18, 436–438 (2022). https://doi.org/10.1038/s41589-022-01021-7
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DOI: https://doi.org/10.1038/s41589-022-01021-7
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