N-Ras lipidation cycling is known to regulate its trafficking and function. A new S-depalmitoylation inhibitor induces N-Ras membrane mislocalization, providing insights into N-Ras function and laying the foundation for a new cancer therapeutic strategy.
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Qiu, T., Dickinson, B.C. A stop sign for RAS trafficking. Nat Chem Biol 17, 840–841 (2021). https://doi.org/10.1038/s41589-021-00789-4
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DOI: https://doi.org/10.1038/s41589-021-00789-4
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