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REDOX BIOLOGY

Redox-coupled rhythm and brews

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A genetically encoded real-time redox reporter reveals that H2O2-signaling peroxiredoxin (PRX) proteins couple yeast metabolic oscillations with the cell division cycle. This new PRX function suggests fresh avenues for exploring circadian regulation of cell division and cancer.

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Fig. 1: Respiratory oscillations impose metabolic checkpoints on cell cycle progression in S. cerevisiae.

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Authors and Affiliations

  1. MRC Laboratory of Molecular Biology, Cambridge, UK

    John S. O’Neill

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  1. John S. O’Neill
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Correspondence to John S. O’Neill.

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The author declares no competing interests.

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O’Neill, J.S. Redox-coupled rhythm and brews. Nat Chem Biol 17, 373–374 (2021). https://doi.org/10.1038/s41589-021-00777-8

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  • DOI: https://doi.org/10.1038/s41589-021-00777-8

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