Yin Yang 1 (YY1) is a transcription factor involved in gene regulation. A recent study has revealed G-quadruplex structures as novel binding targets of YY1, and their interactions regulate DNA looping and gene expression.
This is a preview of subscription content, log in via an institution to check access.
References
Di Antonio, M. et al. Nat. Chem. 12, 832–837 (2020).
Varshney, D., Spiegel, J., Zyner, K., Tannahill, D. & Balasubramanian, S. Nat. Rev. Mol. Cell Biol. 21, 459–474 (2020).
Williams, P., Li, L., Dong, X. & Wang, Y. J. Am. Chem. Soc. 139, 12426–12429 (2017).
Li., L. et al. Nat. Chem. Biol. https://doi.org/10.1038/s41589-020-00695-1 (2020).
Atchison, M. L. Front. Immunol. 5, 45 (2014).
Hyde-DeRuyscher, R. P., Jennings, E. & Shenk, T. Nucleic Acids Res. 23, 4457–4465 (1995).
Houbaviy, H. B., Usheva, A., Shenk, T. & Burley, S. K. Proc. Natl. Acad. Sci. USA 93, 13577–13582 (1996).
Weintraub, A. S. et al. Cell 171, 1573–1588.e28 (2017).
Deng, Z., Cao, P., Wan, M. M. & Sui, G. Transcription 1, 81–84 (2010).
Gordon, S., Akopyan, G., Garban, H. & Bonavida, B. Oncogene 25, 1125–1142 (2006).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Zhao, H., Kwok, C.K. Bringing distant DNA together. Nat Chem Biol 17, 125–126 (2021). https://doi.org/10.1038/s41589-020-00705-2
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41589-020-00705-2
- Springer Nature America, Inc.