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Spatial biology

Charting multicellular tissue structure cell-to-cell

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The spatial biology revolution promises deep insights into tissue organization, but deriving this knowledge from diverse, complex data remains a major obstacle. Data-driven discovery of the multicellular organization of tissues is now achieved by transforming multimodal spatial imaging data using deep learning.

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Fig. 1: CellCharter combines deep learning and spatial clustering to identify local niches.

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Correspondence to H. Raza Ali.

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Schrader, E., Ali, H.R. Charting multicellular tissue structure cell-to-cell. Nat Genet 56, 14–15 (2024). https://doi.org/10.1038/s41588-023-01624-3

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