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The NCI Genomic Data Commons

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An Author Correction to this article was published on 18 May 2021

This article has been updated

The National Cancer Institute (NCI) Genomic Data Commons (GDC) contains more than 2.9 petabytes of genomic and associated clinical data from more than 60 NCI-funded and other contributed cancer genomics research projects. The GDC consists of five applications over a common data model and a common application programming interface.

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Fig. 1: Screenshot of the GDC DAVE tools.
Fig. 2
Fig. 3: Various daily GDC statistics from 1 October 2017 to 30 October 2020.

Change history

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Acknowledgements

This project was funded in part with Federal funds from the National Cancer Institute, National Institutes of Health, agreement 14X050 and task order T02 under agreement 17X147 under contract HHSN261200800001E. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products or organizations imply endorsement by the US Government. The project is grateful for the contributions of S. Marechek and E. Miller, both of whom have passed away.

Author information

Author notes

  1. Vincent Ferretti

    Present address: CHU Sainte-Justine, Universite de Montreal, Montreal, Quebec, Canada

  2. Stuti Agrawal

    Present address: Merck Healthcare, Darmstadt, Germany

  3. Maksim An

    Present address: Microsoft Corporation, Redmond, WA, USA

  4. Justin H. B. Barnowski & Richard Jackson

    Present address: Neighborhoodscom, Chicago, IL, USA

  5. Christian Dompierre

    Present address: Sympatic, Chicago, IL, USA

  6. Michael S. Fitzsimons

    Present address: University of Illinois at Chicago, Chicago, IL, USA

  7. Michael Ford

    Present address: ModelOp, Chicago, IL, USA

  8. Sameera S. George & Bedford L. West

    Present address: BenchPrep, Chicago, IL, USA

  9. Francois Gerthoffert

    Present address: Jahia Solutions, Toronto, Ontario, Canada

  10. Ajinkya Kadam

    Present address: Quantcast, Chicago, IL, USA

  11. Janice Lodato

    Present address: Amount, Chicago, IL, USA

  12. Plamen Martinov

    Present address: Open Commons Consortium, Chicago, IL, USA

  13. Daniel P. Miller

    Present address: Children’s Hospital of Philadelphia, Philadelphia, PA, USA

  14. Mark W. Murphy

    Present address: Cisco, San Jose, CA, USA

  15. Francisco M. Ortuño

    Present address: Clinical Bioinformatics Area Fundacion Progreso y Salud (FPS), Seville, Spain

  16. Jesús Pedrosa

    Present address: Tempus, Chicago, IL, USA

  17. Phuong L. Pham

    Present address: Cole-Parmer, Vernon Hills, IL, USA

  18. Maxim Y. Popov

    Present address: Blink Health, New York, NY, USA

  19. Raymond Powell & Kyle A. Schmitt

    Present address: Argonne National Labs, Argonne, IL, USA

  20. Joseph Sislow

    Present address: Civis Analytics, Chicago, IL, USA

  21. Yajing Tang

    Present address: Google, Chicago, IL, USA

  22. Heather D. Troyer

    Present address: University of Notre Dame, Notre Dame, IN, USA

  23. Chang Wang

    Present address: Appify, San Francisco, CA, USA

  24. Shane Wilson

    Present address: Peyk, Los Angeles, CA, USA

  25. These authors contributed equally: Allison P. Heath, Vincent Ferretti.

  26. These authors jointly supervised this work: Lou Staudt, Robert L. Grossman.

Authors and Affiliations

  1. Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Allison P. Heath

  2. Ontario Institute for Cancer Research, Toronto, Ontario, Canada

    Vincent Ferretti, Rosita Bajari, Jeffrey Burt, Ann Catton, Brandon F. Chan, Kim Cullion, Phuong-My Do, Miyuki Fukuma, Francois Gerthoffert, Sid Joshi, Aishmit Khurana, Kyle M. J. Kim, Koji Miyauchi, Samantha Rich, Bessie Rogel, Lincoln Stein, Chang Wang, Alex Wilmer, Shane Wilson, Kaman Wu, Linda Xiang, Joseph T. Yamada, Christine Yu, Christina K. Yung, Junjun Zhang & Yuanheng Zhao

  3. University of Chicago, Center for Translational Data Science, Chicago, IL, USA

    Stuti Agrawal, Maksim An, James C. Angelakos, Renuka Arya, Bilal Baqar, Justin H. B. Barnowski, Christian Dompierre, Michael S. Fitzsimons, Michael Ford, Gajanan L. Ganji, Sameera S. George, Fauzi Gomez, Kang Han, Richard Jackson, Ajinkya Kadam, Victoria E. Kraft, Shenglai Li, Janice Lodato, Jeffrey A. Mazzone, Daniel P. Miller, Ian Miller, Joshua S. Miller, Mark W. Murphy, Thomas Nullet, Rowland O. Ogwara, Francisco M. Ortuño, Jesús Pedrosa, Phuong L. Pham, Maxim Y. Popov, James J. Porter, Raymond Powell, Karl Rademacher, Colin P. Reid, Jeremiah H. Savage, Kyle A. Schmitt, Trevar J. Simmons, Joseph Sislow, Jonathan Spring, Sean Sullivan, Yajing Tang, Heather D. Troyer, Bedford L. West, William P. Wysocki, Zhenyu Zhang, Ariz Zubair & Robert L. Grossman

  4. Essential Software, Rockville, MD, USA

    Fay Chu & Laxmi Lolla

  5. National Cancer Institute, Bethesda, MD, USA

    Tanja Davidsen, Martin L. Ferguson, Daniela S. Gerhard, Zhining Wang, Liming Yang, Jean Claude Zenklusen & Louis M. Staudt

  6. Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA

    Sharon Gaheen, Biju Issac, Mark A. Jensen, Himanso Sahni & Mathangi Thiagarajan

  7. Center for Research Informatics, University of Chicago, Chicago, IL, USA

    Tzintzuni I. Garcia & Kyle M. Hernandez

  8. Consultant, Columbus, OH, USA

    Tara M. Lichtenberg

  9. University of Chicago, Biological Sciences Division, Information Security Office, University of Chicago, Chicago, IL, USA

    Plamen Martinov

Authors
  1. Allison P. Heath
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  2. Vincent Ferretti
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  3. Stuti Agrawal
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  4. Maksim An
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  17. Christian Dompierre
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  18. Martin L. Ferguson
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  19. Michael S. Fitzsimons
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  20. Michael Ford
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  27. Francois Gerthoffert
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  28. Fauzi Gomez
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  90. Louis M. Staudt
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  91. Robert L. Grossman
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Contributions

The GDC software was developed and tested by A. Khurana, A. Kadam, A.W., A.H., A.C., A.Z., B.F.C., B.L.W., B.R., B.B., C.F.B., C.W., C.D., C.K.Y., C.Y., C.P.R., F. Gomez, F. Gerthoffert, F.C., G.L.G., I.M., J.C.A., J.J.P., J.B., J.A.M., J.P., J. Spring, J. Sislow, J.T.Y., J.S.M., J.Z., J.H.B.B., K.W., K.H., K.R., K.C., K.M., K.M.J.K., K.A.S., L.L., L.X., M.A., M.W.M., M.Y.P., M.S.F., M. Ford, M. Fukuma, P.L.P., P.-M.D., P.M., R.P., R.A., R.L.G., R.B., R.J., R.O.O., S.R., S.S., S.W., S.J., S.A., T.N., T.I.G., V.E.K., V.F., W.P.W., Y.T. and Y.Z. Bioinformatics, data curation and data modeling were performed by A.P.K., D.P.M., F.M.O., J.H.S., J.Z., K.M.H., L.S., M.A.J., M.L.F., R.L.G., R.B., S.L., T.M.L., T.I.G., V.F., W.P.W., Z.Z. and Z.W. The project managers were A.P.H., B.I., C.K.Y., D.S.G., E.M., F.G., H.D.T., H.S., J.L., J.C.Z., L.Y., L. Stein, L. Staudt, M.A.J., M.L.F., M.T., R.L.G., S.S.G., S.G., T.D., T.J.S., V.F. and Z.W. The manuscript was written and revised by A.P.H., D.S.G., J.C.Z., L. Staudt, R.L.G. and Z.Z.

Corresponding author

Correspondence to Robert L. Grossman.

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The authors declare no competing interests.

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Peer review information Nature Genetics thanks the anonymous reviewers for their contribution to the peer review of this work.

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Heath, A.P., Ferretti, V., Agrawal, S. et al. The NCI Genomic Data Commons. Nat Genet 53, 257–262 (2021). https://doi.org/10.1038/s41588-021-00791-5

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