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Copy number signatures in ovarian cancer

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A new study uncovers novel copy number signatures in ovarian cancer genomes. This work sheds light on mutational processes driving ovarian cancer, reveals the distribution of copy number features across the patient population and identifies new genomic properties related to treatment response.

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Fig. 1: Active copy number signatures over time create a composite portrait that can be observed with genome sequencing.

References

  1. Cancer Genome Atlas Research Network. Nature 474, 609–615 (2011).

  2. McIntyre, G. et al. Nat. Genet. https://doi.org/10.1038/s41588-018-0179-8 (2018).

  3. Patch, A.-M. et al. Nature 521, 489–494 (2015).

    Article  CAS  Google Scholar 

  4. McPherson, A. et al. Nat. Genet. 48, 758–767 (2016).

    Article  CAS  Google Scholar 

  5. Wang, Y. K. et al. Nat. Genet. 49, 856–865 (2017).

    Article  CAS  Google Scholar 

  6. Davies, H. et al. Nat. Med. 23, 517–525 (2017).

    Article  CAS  Google Scholar 

  7. Alexandrov, L. B. et al. Nature 500, 415–421 (2013).

    Article  CAS  Google Scholar 

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Correspondence to Sohrab P. Shah.

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S.P.S. is a principal shareholder of Contextual Genomics, Inc.

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Shah, S.P. Copy number signatures in ovarian cancer. Nat Genet 50, 1208–1209 (2018). https://doi.org/10.1038/s41588-018-0212-y

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