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Gene therapy

A retrotransposon for site-specific gene transfer

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An engineered retrotransposon achieves targeted gene transfer into the human genome.

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Fig. 1: Comparison of transposon systems used for transgene integration.

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Authors and Affiliations

  1. Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA

    Fred Dyda & Alison B. Hickman

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  1. Fred Dyda
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  2. Alison B. Hickman
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Correspondence to Fred Dyda.

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The authors declare no competing interests.

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Dyda, F., Hickman, A.B. A retrotransposon for site-specific gene transfer. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02180-9

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  • DOI: https://doi.org/10.1038/s41587-024-02180-9

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