Protein language models learn from diverse sequences spanning the evolutionary tree and have proven to be powerful tools for sequence design, variant effect prediction and structure prediction. What are the foundations of protein language models, and how are they applied in protein engineering?
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J.A.R. and A.M. are employed by Profluent Bio, Inc.
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Ruffolo, J.A., Madani, A. Designing proteins with language models. Nat Biotechnol 42, 200–202 (2024). https://doi.org/10.1038/s41587-024-02123-4
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DOI: https://doi.org/10.1038/s41587-024-02123-4
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