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Regenerative medicine

Survival of the fittest glia

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Human glial progenitors transplanted into a chimeric mouse brain replace sick or older human glia, a finding that could one day lead to new treatments for neurological disease.

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Fig. 1: Young glial progenitor cells (GPCs) can outcompete and replace older and diseased GPCs.

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Authors and Affiliations

  1. Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA

    V. Alexandra Moser & Clive N. Svendsen

Authors
  1. V. Alexandra Moser
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  2. Clive N. Svendsen
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Correspondence to Clive N. Svendsen.

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The authors declare no competing interests.

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Moser, V.A., Svendsen, C.N. Survival of the fittest glia. Nat Biotechnol 42, 700–702 (2024). https://doi.org/10.1038/s41587-023-01944-z

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